The better mitochondria function is responsible for the memory enhancement and improvement in the expression of NSE, GFAP and MBP, and conversely the mitochondria dysfunction is a hallmark of many neurological diseases, including autism spectrum disorder, hyperactivity disorder, schizophrenia, Alzheimer’s disease, Parkinson’s disease, etc. (31). Here, GFAP is linked to early-onset autosomal dominant Alzheimer disease.