Based on the in vitro transcriptome analysis and validation of “cytokine-cytokine receptor interaction,” “PI3K-Akt signaling pathway” and “MAPK signaling pathway,” we measured the relative protein expression of TGFB2, INHBB, PIK3R3, ITGB8, NTRK, and CACNA1D in tumor tissue. The gene discussed is PIK3R3; the disease is neoplasm.