For ERCC1 rs3212986, the significant impact was detected on increased the risk of CRC under allele, homozygous, dominant and recessive models (A vs. C: OR = 1.267, 95% CI = 1.027–1.562, p = 0.027; AA vs. CC: OR = 1.805, 95% CI = 1.276–2.553, p = 0.001; AA+AC vs. CC: OR = 1.214, 95% CI = 1.012–1.455, p = 0.037; AA vs. AC+CC: OR = 1.714, 95% CI = 1.225–2.399, p = 0.002) (Figure 3). Here, ERCC1 is linked to colorectal carcinoma.