Head and neck cancer: SELENBP1 is downregulated in head and neck squamous cell carcinoma (HNSCC) including nasopharyngeal carcinoma (NPC), laryngeal cancer (LC), oral cancer (OC), tonsil cancer (TC), and hypopharyngeal cancer (HPC), which have no association with tumor T-stage, N-stage, and tumor grade. The gene discussed is SELENBP1; the disease is nasopharyngeal carcinoma.