RNPC3 and non-small cell lung carcinoma: In this study, we searched for differential genes through gene expression data published in GEO, and explored possible pathways using Disease Ontology (DO), Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis after normalization of differential genes; further screened and validated potential signature genes RHEBL1 and RNPC3 in non-small cell lung cancer.