CD8A and bladder transitional cell carcinoma: These three cell types may be involved in enhancing the survival of patients in the ICD cluster B. The vast majority of immune cells showed increased infiltration in ICD cluster A, including not only immune cells (macrophages and mast cells) associated with poorer prognosis in BLCA but also those associated with better prognosis (type 1 T helper cells, regulatory T cells and activated CD8 T cells).