In brief, GO and KEGG enrichment analysis results suggested that HSSD treats influenza mainly through combining multiple components with multiple influenza virus proteins, acting on multiple targets, and regulating multiple pathways, which include inflammatory response, immune response, cell apoptosis and influenza virus replication, as well as the IL-17, TNF, PI3K-Ak, and Toll-like receptor signaling pathways to achieve the effect of treatment of influenza. This evidence concerns the gene ADK and influenza.