TP53 and cancer: Some species of Mycoplasmas, including M. fermentans, are associated with cancers (Ainsworth et al., 2001; Barykova et al., 2011; Henrich et al., 2014) and we previously demonstrated that Mycoplasma infection promoted lymphoma in a mouse model and its DnaK, a chaperone protein belonging to the HSP70 family, interacts with key cellular proteins to hamper essential pathways related to DNA repair and p53 functions (Zella et al., 2018).