Similarly, recent data from Myocardial Ischemia Detection By Circulating Biomarkers (MYOMARKER) study showed attenuated flow-citometry-based platelet reactivity to P2Y12 inhibitor (mainly clopidogrel) among female outpatients with suspected myocardial ischemia when compared to men (38). This evidence concerns the gene P2RY12 and myocardial ischemia.