One hundred twenty-seven signaling pathways were obtained via KEGG pathway enrichment analysis, including lipid and atherosclerosis, chemical carcinogenesis receptor activation, hepatitis B, fluid shear stress, atherosclerosis, kaposi sarcoma−associated with hepatitis, virus infection, apoptosis, and TNF signaling pathway (Supplementary Table S3; Figures 2C,D). The gene discussed is TNF; the disease is atherosclerosis.