Previously, miR-34a was reported to inhibit tumor angiogenesis in endothelial cells, and the neurogenic locus notch homolog protein 1 (Notch1) pathway has been reported to play an important role in vascular endothelial growth factor (VEGF)-treated angiogenesis (Liu et al., 2003; Kumar et al., 2012). This evidence concerns the gene NOTCH1 and neoplasm.