A study examined the inhibitory effect of tubulin inhibitor STK899704 on colon cancer cell migration and CSC stemness and showed that STK899704 downregulated the mRNA expression levels of the cell migration mediator focal adhesion kinase (FAK) and suppressed MAPK and ERK, which are downstream signaling molecules of FAK. The gene discussed is MAPK1; the disease is malignant colon neoplasm.