NOTCH1 and ovarian carcinoma: Through the Akt and Notch-1 signaling pathways, theaflavin-3,3′-digallate inhibited the angiogenesis in a human umbilical vein endothelial cell and a chick chorioallantoic membrane model, induced by human ovarian cancer cells (OVCAR-3) (Gao et al., 2016).