SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: We have recently reported that a series of acidic biosynthetic precursor molecules found in cannabis display anticonvulsant properties in the Scn1a+/− mouse model of Dravet syndrome, including CBGVA and CBDVA (Anderson et al., 2019; Anderson et al., 2021a; Anderson et al., 2021b).