AIM2 and neoplasm: After six rounds of intravesical treatments of BCG every 5 days, a prolonged survival was observed among mice inoculated with AIM2-overexpressed cells compared to control mice: after 30 days post-inoculation, seven out of ten control tumor-bearing mice died, whereas only two out of ten AIM2-overexpressed tumor-bearing mice died (Figures 5A,B).