IL1B and nasopharyngeal carcinoma: Although IL-1β is often considered pro-tumourigenic, especially in chronic inflammatory conditions (Shadpour et al., 2019), inflammasome and IL-1β-mediated antitumor activity have also been demonstrated in NPC and hematopoietic cells, consistent with our foundings (Ghiringhelli et al., 2009; Allen et al., 2010; Chen et al., 2012).