FMR1 and Anxiety: Beside these considerations, our data highlight the relevance of the early timing of stress exposure: the comparison with previous findings obtained from Fmr1-KO mice with post-natal stress (Qin et al., 2011; Lemaire-Mayo et al., 2017) indeed suggests a more marked impact of the pre-natal stressful experience, with more pronounced and varied behavioral effects; anxiety levels were for example enhanced here in KO stressed mice, while they were unaltered following post-natal stress exposure (Qin et al., 2011; Lemaire-Mayo et al., 2017).