Similarly, an inconsistent anxiety-like profile of adult Fmr1 mutants was previously described in the elevated plus maze, in line with the one observed here, i.e., more often characterized by unaltered (e.g., Mineur et al., 2002; Nielsen et al., 2002; Zhao et al., 2005; Pietropaolo et al., 2011) or reduced (e.g., de Diego-Otero et al., 2009; Eadie et al., 2009; Liu et al., 2011; Qin et al., 2011; Heulens et al., 2012; Jung et al., 2012; Hebert et al., 2014) anxiety levels in this test. Here, FMR1 is linked to Anxiety.