To determine the role of KvS subfamilies in NSCLC, we explored the lung cancer datasets from The Cancer Genome Atlas (TCGA) to inquire expression levels of KCNF1 (Kv5.1), KCNG4 (Kv6.4), KCNV2 (Kv8.2), and KCNS1 (Kv9.1). This evidence concerns the gene KCNS1 and lung cancer.