ARID1A and tuberculosis: To further identify enriched pathways perturbed by Arid1a haploinsufficiency, we subjected the differentially expressed genes (DEGs) to Kyoto Encyclopedia and Genes and Genomes (KEGG) analysis and found that the upregulated genes were more connected to inflammatory signatures such as tuberculosis, phagosome, synthesis, and degradation of ketone bodies (Fig EV3D).