To determine whether ZFP36/ZFP36L1 were limiting factors for cytotoxic CD4+ T cells in vivo, we infected Zfp36fl/fl/Zfp36l1fl/flCd4cre mice with influenza A virus (PR8 H1N1) and measured CD4+ T cells in the lung 10 days following infection. Here, ZFP36 is linked to infection.