The levels of other parameters: estradiol, prolactin, 17-OH-progesterone, LH, FSH, SHBG, testosterone, BAT%, FAI%, androstendione, vitamin D, calcitonin, parathyroid hormone, osteoprotegerin, sRANKLt, leptin, BMD total, BMD L1-L4, T-score, Z-score, BMI, BMC, AG, TBS and glucose in women with hyperandrogenism in relation to the distribution of genotypes of the ESR1 rs3020314 polymorphism did not show any significant statistical differences. The gene discussed is LEP; the disease is hyperandrogenism.