The concentration of other parameters: prolactin, LH, FSH, SHBG, testosterone, DHEA-SO4, glucose, insulin, vitamin D, vitamin 25(OH)D, calcitonin, parathyroid hormone, osteoprotegerin, sRANKL, leptin and other parameters: BAT%, FAI%, BMD total, BMD L1-L4, T-score, Z-score, BMI, BMC, VF and TBS in women with hyperandrogenism in relation to the distribution of genotypes of the ESR1 rs1884051 polymorphism did not show any significant statistical differences (Tables 2, 3, 4, 5, 6). The gene discussed is TNFRSF11B; the disease is hyperandrogenism.