Analysis of the cervicovaginal self-samples of 27 patients with ovarian cancer identified six patients (22%) with a total of seven (potentially) pathogenic variants: PIK3CA (n=3), TP53 (n=2), and ARID1A (n=2); 98% of the exons were ‘adequately sequenced’. The gene discussed is ARID1A; the disease is ovarian cancer.