Each SD higher circulating levels of IP10 (NSNP = 1) was associated with higher risk of psoriasis and IBD (IP10→psoriasis: ORWald 2.97; 95% CI 1.74–5.05; pWald = 6.3 × 10−5; IP10→IBD: ORWald 1.67; 95% CI 1.42–1.97; pWald = 1.3 × 10−9), but lower risk of Crohn disease and UC (IP10→Crohn: ORWald 0.50; 95% CI 0.38–0.66; pWald = 5.7 × 10−7; IP10→UC: ORWald 0.54; 95% CI 0.41–0.70; pWald = 5.4 × 10−6). Here, CXCL10 is linked to psoriasis.