CXCL9 and Alzheimer disease: Chemokines have been found to involve in both neuroinflammatory and neurodegenerative processes and play a role in the development of Aβ plaques and neurofibrillary tangles, 2 pathologic hallmarks of AD.38 However, colocalization in our study only supported common causal SNPs for MIG and Crohn disease, indicating that the association between MIG and AD may be confounded by linkage disequilibrium.