For genes with multiple identified non-coding variants, they are enriched in biological pathways related to neural systems, including glutamatergic synapse (FDR = 0.0053) and axon guidance (FDR = 0.0053); cardiovascular system (cardiomyopathy, FDR = 0.0053); and pathways related to tumorigenesis, such as phospholipase D signaling pathway (FDR = 0.0053), ErbB signaling pathway (FDR = 0.033) and Cadherin signaling pathway (FDR = 0.015). This evidence concerns the gene EGFR and cardiomyopathy.