This demonstrated that HNF4α immunopositivity correlated with classified single or binucleated hepatocytes; there was no HNF4α immunopositivity in nuclei of cells classified as ‘‘non-hepatocytes/other.’’ The normal sinusoidal architecture in livers of animals with disseminated infection was visible from the normal hepatic autofluorescence (Figures 2I and S4). The gene discussed is HNF4A; the disease is infection.