MAP3K15 and metabolic syndrome: Curiously, MAP3K15 was only associated with reduced glucose (β = −0.11 SD units, 95% CI: [−0.16, −0.06], P = 7.2 × 10−5) and none of the other metabolites, including those that tend to be deranged in metabolic syndromes, such as triglycerides, LDL cholesterol, and high-density lipoprotein cholesterol (table S25).