However, MAP3K15 appears to be conspicuously specific for glucose metabolism, with little to no effect on other aspects of metabolic syndrome such as blood pressure, BMI, total body fat mass, or body fat percentage in both the UKB and MCPS (Figs. 1, C and D, and 2, C and D, and tables S19 and S24). The gene discussed is MAP3K15; the disease is metabolic syndrome.