CHMP5 and infection: To investigate how salivary proteases contribute to SARS-CoV-2 entry, we determined entry efficiency of SARS-CoV-2 into Calu-3 cells upon pretreatment of virions with pools of saliva from 3 healthy donors (without recent infection and/or vaccination to exclude the possibility of mucosal anti-spike antibodies) (Fig 6G and S1 Table).