PROCR and malaria: In non-pregnant women, infected erythrocyte sequestration is mediated by PfEMP1 that can bind to endothelial receptors such as Endothelial Protein C Receptor (EPCR), Intracellular Adhesion Molecule 1 (ICAM-1) or CD36, which has been associated with severe malaria in immunologically naïve hosts (children) and asymptomatic infections in semi-immune hosts, respectively [7].