Interestingly, we demonstrated that all the three haplotypes (A-G, GA-GA and G-T-T) in PSORS1C3 gene, the AG-CT-C haplotype in CARD14 gene and the T-T-T haplotype in TLR4 gene were detected at higher frequencies in patients with psoriasis compared to controls (Table 3). This evidence concerns the gene TLR4 and psoriasis.