And the results demonstrated that the mRNA expression of the hub targets included STAT3, CXCL8, CXCL12, IL6, RELA, EGFR, TP53, and PTPN11 were all upregulated in the MG rats compared to the BG rats, and JFFZLZ treatment could downregulate these genes expression compared to MG rats (Figure 7(B)). The gene discussed is IL6; the disease is myasthenia gravis.