USP1 and head and neck squamous cell carcinoma: The sensitivity of tumors to cisplatin mainly depends on the ability of cisplatin to recognize and repair DNA damage.[35, 36] Based on the discovery and confirmation that SERPINB3 regulates the cisplatin sensitivity of HNSCC through DNA damage repair, we identified USP1, which interacts with SERPINB3, by Co‐IP and mass spectrometry.