USP1 and head and neck squamous cell carcinoma: USP1 is a member of the deubiquitinating enzyme family that can bind USP1‐associated factor to form a protein complex and participate in the regulation of DNA damage responses, mainly the FA pathway and TLS repair.[37, 38] Our study found that SERPINB3 in HNSCC cells could undergo cytonuclear translocation and colocalize with USP1 after treatment with cisplatin.