Moreover, IHC staining of tumor tissue showed that the expression of Ki‐67, a marker of proliferation, was decreased in the PT100 group, the expression of the EMT‐related marker N‐cadherin was decreased, and the expression of E‐cadherin was increased in the PT100‐treated group of BALB/c nude mice (Figure 6D). Here, CDH2 is linked to neoplasm.