Intriguingly, hsa-miR-132 may bind to SNCA mRNA as evidenced by publicly available next-generation sequencing-based high-throughput sequencing of RNA isolated by cross-linking immunoprecipitation data in the human brain.24 Further functional studies focusing on miR-132-3p/-5p and miR-129-5p need to elucidate the underlying Parkinson’s disease pathomechanisms while also considering possibly shared pathomechanisms with Alzheimer’s disease (also see Supplementary Note for previous knowledge on hsa-miR-132-3p/-5p and miR-129-5p). Here, SNCA is linked to early-onset autosomal dominant Alzheimer disease.