TGFB1 and neoplasm: TGFβ suppresses the expression of MHC-I and genes encoding the antigen-processing and -presentation machinery, and TGFβ blockade has been shown to reepithelialize aggressive carcinomas to elevate the expression of MHC-I and antigen presentation and enhance tumor visibility to antigen-specific cytotoxic T cells (Dodagatta-Marri et al. 2019, Lind et al. 2020).