Targeting the myeloid population in GBM, however, is complicated by the presence of both resident microglia and infiltrating tumor-associated macrophages, which may have diverging roles in GBM.26 Therefore, it is imperative that future studies associate the OATP isoforms to each myeloid population using microglia-specific markers, such as P2RY12 and TMEM119.26 The gene discussed is P2RY12; the disease is glioblastoma.