Recently, Yang and colleagues, reported that a KD was effective as an chemotherapy adjuvant reducing tumor growth in syngeneic subcutaneous pancreatic tumors and prolonged survival in the clinically relevant LSL-KrasG12D/+, LSL-Trp53R172H/+, Pdx1-Cre (KPC) genetically engineered mouse model of pancreatic cancer (17). The gene discussed is PDX1; the disease is pancreatic neoplasm.