These authors also concluded that this reduced proliferative activity of nucleated erythroid cells at diagnosis may result in future transfusion-dependence in MDS patients.11 In the underlying study, the Ki-67 proliferation index of nucleated erythroid cells in the BM was identified as a potential parameter for prediction of future transfusion-dependence in MDS patients in addition to Hb levels. The gene discussed is MKI67; the disease is myelodysplastic syndrome.