PCSK9 and breast cancer: They showed that the cells treated with low FD showed the highest reduction in PCSK9 mRNA at the end of the 24-hour treatment period, closely followed by the cells treated with high-FD, and ultimately by the cells treated with BC-NP, while the untreated cells showed the most significant expression of PCSK9 mRNA (Ochin and Garelnabi, 2018[41]).