The following seventeen blood marker variables were chosen to predict the status of prevalent MCI and AD: CRP, FABP3, IL_10, IL_6, Ab40, Ab42, Tau, NFL, PPY, sICAM_1, sVCAM_1, TNF_alpha, GLP_1, Glucagon, PYY, Insulin, and HOMA_IR (Table 2). The gene discussed is PPY; the disease is Alzheimer disease.