However, we detected neither significant changes in tumor-infiltrating CD8+ cytotoxic T cells or CD4+ Th cells nor differences in natural killer cells, macrophages, or myeloid-derived suppressor cells between WT and GLSECKO in both E0771 and MMTV-PyMT tumors (Supplementary Fig. S3A–S3L). The gene discussed is CD8A; the disease is neoplasm.