In the non-hyperlipidemic group, thirteen independent variables (age, sex, smoking status, drinking history, family history, hypertension, diabetes mellitus, homocysteine, vitamin B12 and CTRP9, HMW, MMW, LMW) were included in the binary logistic regression for analyzing ischemic stroke risk factors. The gene discussed is C1QTNF9; the disease is Hypertension.