We also observed that the exon inclusion level profiles of the blastemal-predominant Wilms’ tumor patient-derived xenografts are typically closer to hFK1—the most immature fetal cell fraction—than to the other more mature fetal cell fractions (hFK2 and hFK3), similar to what we have seen in gene expression (Fig. 2A). Here, FOXG1 is linked to Nephroblastoma.