BAIAP3 and acute lymphoblastic leukemia: For validation, we performed real-time quantitative PCR in our extended cohort of 13 KMT2A-rearranged infant ALL cellular models on three genes, MMP15, BAIAP3 and CD82, confirming significant upregulation of these genes via hypomethylation following treatment with decitabine (Supplementary Fig. 6F).