For example, cg11554650 (PPP1R18), a BMI-associated CpG on chromosome 6, colocalized with type 2 diabetes at SNP rs2516396 (PPFC = 0.98), which explained 100% of the observed PPFC; cg05337441 (APOB), an LDL-associated CpG at chromosome 2, colocalized with coronary artery disease at rs668948 (PPFC = 0.8), which explained 41% of the observed PPFC; and cg03676485 (LFNG), a HDL-associated CpG at chromosome 7, colocalized with systolic and diastolic BP at rs4632959 (PPFC = 0.99), which explained 100% of the observed PPFC. The gene discussed is PPP1R18; the disease is type 2 diabetes mellitus.