In addition to the MM driver genes (e.g., CCND1, LAMP5, and TNFRSF17)19 and quadruple therapy resistance genes (e.g., NPM1 and MYC)22, we discovered upregulated DEGs in SORs (e.g., MS4A1, RACK1, UQCRH, and SQSTM1). The gene discussed is MS4A1; the disease is Miyoshi myopathy.