Genetic analysis indicated significant enrichment of common AF risk variants around STS (7 065 298–7 272 682 bp in GRCh37/hg19 genome build) in males, and of common GI disorder and asthma/anaemia risk variants around PNPLA4 (7 866 804–7 895 780 bp) in males and females, respectively. Here, PNPLA4 is linked to asthma.