It has been used in treating autoimmune diseases due to its immunomodulatory effects on various cytokines, including interleukin-1 (IL-1) and IL-6.13 Hydroxychloroquine was shown to be effective against SARS-CoV-2 in invitro studies, but its use was discontinued in later studies due to its lack of antiviral activity against SARS-CoV-2 and its cardiotoxic effects.14 In our center, 132 (26.4%) patients were treated with HCQ, and 12 (9%) were mortal. The gene discussed is IL6; the disease is autoimmune disease.