Ameloblastic fibrodentinoma (AFD) and ameloblastic fibroodontoma (AFO) are classified as developing odontomas, although the prevalence of BRAF p.V600E mutations in AFD and AFO is similar to ameloblastic fibroma (AF) but differs from odontoma, which lacks BRAF p.V600E mutations [11]. The gene discussed is BRAF; the disease is Nager acrofacial dysostosis.