Strikingly, we observed a significant tumor burden accompanied by high BCL6 expression in mouse lung lesions 4 months after intranasal administration of adenovirus-Cre (Ad-Cre) (Supplemental Figure 1, A and B; supplemental material available online with this article; https://doi.org/10.1172/JCI161308DS1). This evidence concerns the gene BCL6 and neoplasm.