In the training cohort, the univariate analysis identified eight variables including age (P = 0.002), TBIL (P < 0.001), ALB (P = 0.018), INR (P = 0.038), Cr (P = 0.013), HGB (P = 0.025), HE (P < 0.001), SIRS (P < 0.001) (Table 3). The gene discussed is CYGB; the disease is systemic inflammatory response syndrome.