To verify the function of PVT1 in lung cancer cells, we also detected the expression levels of PVT1 in four lung cancer cell lines (A549, H1299, H1975, PC9) and 16HBE and found that PVT1 was also highly expressed in H1975 and A549 cells (Additional file 1: Fig. S6). Here, PVT1 is linked to lung cancer.