ALKBH5 and lung carcinoma: We then detected the expression of ALKBH5 in four lung cancer cell lines (A549, H1299, H1975, PC9) and human bronchial epithelial cell line (16HBE), and found that ALKBH5 was more highly expressed in H1975 and A549 cells than in 16HBE cells (Fig. 1D).